Smart Hybrid Materials (SHMs)
Khashab Research Group
Innovatively Functionalized Nanomaterials for Biomedical, Sensing and Composites Applications

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Microwave-Assisted Solid-Phase Peptide Synthesis Utilizing N-Fmoc-Protected (α-Aminoacyl)- benzotriazoles

Khashab, N. M.; Yoshioka, M.; Haase, D. N.; Wilson, K. R.; Johnson, J. V.; Chung, A.; Haskell-Luevano, C.; Katritzky, A. R. Microwave-Assisted Solid-Phase Peptide Synthesis Utilizing N-Fmoc-Protected (α-Aminoacyl)benzotriazoles. Chem. Biol. Drug Des. 2007, 70, 465-468
Khashab, N. M.; Yoshioka, M.; Haase, D. N.; Wilson, K. R.; Johnson, J. V.; Chung, A.; Haskell-Luevano, C.; Katritzky, A. R.
Microwave irradiation, N-Fmoc-protected(a-aminoacyl) benzotriazole, peptides, Rink amide resin, solid-phase peptide synthesis
2007
A novel microwave-assisted solid-phase peptide synthesis utilizing N-Fmoc-protected(a-aminoacyl)benzotriazoles was applied in the preparation of tri-, tetra-, penta-, hexa-, and heptapeptides in 71% average crude yield.