Smart Hybrid Materials (SHMs)
Khashab Research Group
Innovatively Functionalized Nanomaterials for Biomedical, Sensing and Composites Applications

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Self-Assembled Lipoprotein Based Gold Nanoparticles for Detection and Photothermal Disaggregation of beta-Amyloid Aggregates

Martins, P.; Alsaiari, S.; Julfakyan, K.; Nie, Z.; Khashab, N. M. Self-Assembled Lipoprotein Based Gold Nanoparticles for Detection and Photothermal Disaggregation of beta-Amyloid Aggregates. Chem. Commun. 2017, 53, 2102-2105
Martins, P.; Alsaiari, S.; Julfakyan, K.; Nie, Z.; Khashab, N. M.
Lipoprotein, gold nanoparticles, beta-amyloid aggregates
2017
​We present a reconstituted lipoprotein-based nanoparticles platform comprising a curcumin fluorescent motif and NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.
 
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