Smart Hybrid Materials (SHMs)
مختبر شمس لعلوم النانو
Self-Assembled Nanomaterials for Biomedical, Sensing and Separation Applications

People

Patricia Martins, Ph.D.

Postdoctoral Fellows

Postdoctoral Fellow (Subgroup III: Biomaterials)

Research Interests

My research interests include the Blood-Brain barrier permeation, drug delivery systems and their interaction with biomembranes, the kinetics and thermodynamics of the interaction of drugs and drug carriers with lipidic membranes and the understanding of the mechanisms underlying loading and release of functional molecules into and from their carriers.

Selected Publications


  • Martins, P.; Alsaiari, S.; Julfakyan, K.; Nie, Z.; Khashab, N. M. Self-Assembled Lipoprotein Based Gold Nanoparticles for Detection and Photothermal Disaggregation of beta-Amyloid Aggregates. Chem. Commun. 2017, DOI: 10.1039/C6CC09085K
  • Omar, H.; Croissant, J. G.; Alamoudi, K.; Alsaiari, S.; Alradwan, I.; Majrashi, M. A.; Anjum, D. H.; Martins, P.; Moosa, B.; Almalik, A.; Khashab, N. M. Biodegradable Magnetic Silica@Iron Oxide Nanovectors with Ultra-Large Mesopores for High Protein Loading, Magnetothermal Release, and Delivery. Journal of Controlled Release 2016, DOI: 10.1016/j.jconrel.2016.11.032
  • F. M. Coreta-Gomes, P. A. T. Martins, A. Velazquez-Campoy, W. L. C. Vaz, C. F. G. Geraldes, M. J. Moreno Interaction of bile salts with model membranes mimicking the gastrointestinal epithelium: A study by isothermal titration calorimetry Langmuir 2015, 31, 9097-9104
  • P. T. Martins, A. Velazquez-Campoy, W. L. C. Vaz, R. M. S. Cardoso, J. Valerio, M. J. Moreno Kinetics and thermodynamics of Chlorpromazine interaction with lipid bilayers: effect of charge and cholesterol. J. Am. Chem. Soc. 2012, 134, 4184-4195

Education


  • ​Ph.D., Biological Chemistry, Faculty of Science and Technology, University of Coimbra, Coimbra, Portugal, 2013
  • B.Sc. (Pre-Bologna), Biochemistry, Faculty of Sciences, University of Lisbon, Lisbon, Portugal, 2008

Professional Profile

  • 2015 - 2017: Postdoctoral fellow, Smart Hybrid Materials group, KAUST, Thuwal, Saudi Arabia
  • 2014: Postdoctoral fellow, 3B’s group, University of Minho, Braga, Portugal
  • 2013: Graduate research assistant, QOPNA group, University of Aveiro, Aveiro, Portugal
  • 2009-2011: PhD visiting student, BIFI, University of Zaragoza, Zaragoza, Spain
  • 2008-2013: PhD student, Biological Chemistry group, University of Coimbra, Coimbra, Portugal
  • 2007: Graduate research assistant, Biological Chemistry group, University of Coimbra, Coimbra, Portugal


Scientific and Professional Memberships

  • Biophysical Society (USA)
  • Portuguese Biophysical Society (Portugal)
  • Portuguese Biochemical Society (Portugal)


Awards

  • 2014 – Young Biophysicist 2014 by the Portuguese Biophysical Society
  • 2010 – Best Poster Awardee at the IV Spanish Portuguese Biophysical Congress (Spain) from the Spanish Biophysical Society
  • 2009 & 2011 – International Travel Awardee from the Biophysical Society (USA) to attend the annual meetings

KAUST Affiliations

  • Advanced Membranes and Porous Materials Center (AMPMC)
  • Division of Physical Science and Engineering (PSE)