Smart Hybrid Materials (SHMs)
Khashab Research Group
Innovatively Functionalized Nanomaterials for Biomedical, Sensing and Composites Applications

Publication-7

C-Imidoylation of Esters, Sulfones, Sulfoxides, Amides and Nitro Compounds

Khashab, N. M.; Singh, A.; Katritzky, A. R. C-Imidoylation of Esters, Sulfones, Sulfoxides, Amides and Nitro Compounds. Arkive of Org. Chem. 2007, 5, 263-276
Khashab, N. M.; Singh, A.; Katritzky, A. R.
C-imidoylation, nitro compounds
2007
C-Imidoylation of esters, sulfones, sulfoxides, amides, and nitro- compds. with N-imidoylbenzotriazoles gave β-enamino esters, β-imino sulfones, β-enamino sulfoxides, β-imino amides, and α-nitro enamines resp. in good yields. Strong electron-withdrawing substitutes (esters, sulfoxides, nitroethane) tended to give enamines due to increased acidity of the α-protons, while weak electron-withdrawing substitutes(sulfones, amides) gave imines instead.