Nanocluster capped mesoporous nanoparticles, methods of making and use

by ALsaiari, Shahad, Hammami, Mohamed Amen, Khashab, Niveen M.
Year: 2018

Bibliography

Patent: ALsaiari, Shahad; Hammami, Mohamed Amen; Khashab, Niveen M. Nanocluster capped mesoporous nanoparticles, methods of making and use. PCT Int. Appl. (2018), WO 2018065884 A1 20180412.

Abstract

​Embodiments of the present disclosure describe a conjugate comprising a mesoporous nanoparticle having a plurality of pores, wherein the mesoporous nanoparticle is positively charged, wherein an active agent is disposed in the pore; and a plurality of metal nanoclusters, wherein the metal nanocluster has a negative charge, wherein a gate agent is attached to the metal nanocluster. Embodiments of the present disclosure also describe a method of using a conjugate comprising exposing a conjugate to microbes sufficient to release an active agent and treating the microbes with the released active agent. Embodiments of the present disclosure further describe a method of using a conjugate comprising exposing a conjugate to microbes and detecting a presence of the microbes.

Keywords

Smart Coating Antibacterial Antimicrobial