pH-Responsive Mechanised Nanoparticles Gated by Semirotaxanes

by Khashab, N. M., Belowich, M. E., Trabolsi, A., Friedman, D. C., Valente, C., Lau, Y., Khatib, H. A., Zink, J. I., Stoddart, J. F.

Year: 2009

Bibliography

Khashab, N. M.; Belowich, M. E.; Trabolsi, A.; Friedman, D. C.; Valente, C.; Lau, Y.; Khatib, H. A.; Zink, J. I.; Stoddart, J. F. pH-Responsive Mechanised Nanoparticles Gated by Semirotaxanes. Chem. Commun. 2009, 36, 5371-5373

Abstract

A [2]pseudorotaxane-based mechanized nanoparticle system, which operates within an aq. acidic environment, has been prepd. and characterized; this integrated system affords both water-sol. stalk and ring components in an effort to improve the biocompatibility of these promising new drug delivery vehicles.

Keywords

pH-responsive Mechanised Nanoparticles Semirotaxanes