pH-Responsive Mechanised Nanoparticles Gated by Semirotaxanes

by Khashab, N. M., Belowich, M. E., Trabolsi, A., Friedman, D. C., Valente, C., Lau, Y., Khatib, H. A., Zink, J. I., Stoddart, J. F.
Year: 2009


Khashab, N. M.; Belowich, M. E.; Trabolsi, A.; Friedman, D. C.; Valente, C.; Lau, Y.; Khatib, H. A.; Zink, J. I.; Stoddart, J. F. pH-Responsive Mechanised Nanoparticles Gated by Semirotaxanes. Chem. Commun. 2009, 36, 5371-5373


A [2]pseudorotaxane-based mechanized nanoparticle system, which operates within an aq. acidic environment, has been prepd. and characterized; this integrated system affords both water-sol. stalk and ring components in an effort to improve the biocompatibility of these promising new drug delivery vehicles.


pH-responsive Mechanised Nanoparticles Semirotaxanes